The third episode of 12 Monkeys Season 1 is titled ‘Cassandra Complex’.

A Cassandra Complex is a psychological phenomenon in which an individual’s accurate prediction of a crisis is ignored or dismissed. source: wikipedia

The term is derived from Greek mythology and the Greek Princess Cassandra, daughter of Priam, who was the King of Troy. Enchanted by Cassandra’s beauty, the god Apollo gifted her with the ability to foresee the future. However, when she rebuffed his romantic advances he took revenge by cursing her, so no one would ever believe her visions. Thus, Cassandra was fated to know the future including the fall of Troy and her own death, but because no one believed that she did, was unable to change fate.

After learning of the impending plague from Cole in 2013, 12 Monkeys Cassandra is left alone for 2 years, and we learn that this knowledge will gradually destroy her reputation and career.  In episode three, Cassie is in Haiti trying to stop the outbreak of an unknown virus. Haunted by the prophecy which Cole has given her, she assumes that she is at ground zero of the plague outbreak. Other doctors working with Cassie don’t believe her prediction and when she is proven wrong, Cassie’s self confidence is again shaken.